{"symbol":"GRIK3","synonyms":["GLUR7A","EAA5","GLUR7","GLR7","GLUK3"],"name":"glutamate receptor, ionotropic, kainate 3","description":"Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2899,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2899","proteins":[{"symbol":"GRIK3_HUMAN","href":"/api/1.0/protein/GRIK3_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"},{"name":"Glutamate receptors","href":"/api/1.0/gene_family/Glutamate+receptors"}]}