{"symbol":"GRIN1","synonyms":["MRD8","NMDAR1","NMD-R1","NMDA1","NDHMSD","NDHMSR","GLUN1","NR1"],"name":"glutamate receptor, ionotropic, N-methyl D-aspartate 1","description":"The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":2902,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2902","proteins":[{"symbol":"NMDZ1_HUMAN","href":"/api/1.0/protein/NMDZ1_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"},{"name":"Glutamate receptors","href":"/api/1.0/gene_family/Glutamate+receptors"}]}