{"symbol":"GRK4","synonyms":["GPRK2L","GRK4A","GPRK4","IT11"],"name":"G protein-coupled receptor kinase 4","description":"This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating its deactivation. This gene has been linked to both genetic and acquired hypertension. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]","ncbiEntrezGeneId":2868,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2868","proteins":[{"symbol":"GRK4_HUMAN","href":"/api/1.0/protein/GRK4_HUMAN"}],"hgncRootFamilies":[]}