{"symbol":"GSTT1","synonyms":[],"name":"glutathione S-transferase theta 1","description":"The protein encoded by this gene, glutathione S-transferase (GST) theta 1 (GSTT1), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2015]","ncbiEntrezGeneId":2952,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2952","proteins":[{"symbol":"GSTT1_HUMAN","href":"/api/1.0/protein/GSTT1_HUMAN"}],"hgncRootFamilies":[{"name":"Glutathione S-transferases (GST)","href":"/api/1.0/gene_family/Glutathione+S-transferases+%28GST%29"}]}