{"symbol":"GTF2H5","synonyms":["TTDA","BA120J8.2","TTD3","TFB5","TTD-A","TGF2H5","C6ORF175"],"name":"general transcription factor IIH, polypeptide 5","description":"This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. [provided by RefSeq, Mar 2009]","ncbiEntrezGeneId":404672,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/404672","proteins":[{"symbol":"TF2H5_HUMAN","href":"/api/1.0/protein/TF2H5_HUMAN"}],"hgncRootFamilies":[{"name":"General transcription factors (GTF)","href":"/api/1.0/gene_family/General+transcription+factors+%28GTF%29"}]}