{"symbol":"GUCY1A2","synonyms":["GC-SA2","GUC1A2"],"name":"guanylate cyclase 1, soluble, alpha 2","description":"Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3\u0027,5\u0027-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]","ncbiEntrezGeneId":2977,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2977","proteins":[{"symbol":"GCYA2_HUMAN","href":"/api/1.0/protein/GCYA2_HUMAN"}],"hgncRootFamilies":[{"name":"Guanylate cyclases (GUCY)","href":"/api/1.0/gene_family/Guanylate+cyclases+%28GUCY%29"}]}