{"symbol":"GYPC","synonyms":["GYPD","CD236","GPC","PAS-2\u0027","GE:GPC:GPD:GYPD","CD236R"],"name":"glycophorin C (Gerbich blood group)","description":"Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":2995,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2995","proteins":[{"symbol":"GLPC_HUMAN","href":"/api/1.0/protein/GLPC_HUMAN"}],"hgncRootFamilies":[{"name":"Blood group antigens","href":"/api/1.0/gene_family/Blood+group+antigens"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"}]}