{"symbol":"GZMH","synonyms":["CGL-2","CSP-C","CTLA1","CTSGL2","CCP-X"],"name":"granzyme H (cathepsin G-like 2, protein h-CCPX)","description":"This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14. [provided by RefSeq, Nov 2015]","ncbiEntrezGeneId":2999,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2999","proteins":[{"symbol":"GRAH_HUMAN","href":"/api/1.0/protein/GRAH_HUMAN"}],"hgncRootFamilies":[]}