{"symbol":"H2AFV","synonyms":["H2AV","H2A.Z-2"],"name":"H2A histone family, member V","description":"Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. Several transcript variants encoding different isoforms, have been identified for this gene. [provided by RefSeq, Oct 2015]","ncbiEntrezGeneId":94239,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/94239","proteins":[{"symbol":"H2AV_HUMAN","href":"/api/1.0/protein/H2AV_HUMAN"}],"hgncRootFamilies":[{"name":"Histones","href":"/api/1.0/gene_family/Histones"}]}