{"symbol":"H4C16","synonyms":[],"name":"H4 histone 16","description":"Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq, Aug 2015]","ncbiEntrezGeneId":121504,"ncbiEntrezGeneUrl":"https://ncbi.nlm.nih.gov/gene/121504","proteins":[],"hgncRootFamilies":[]}