{"symbol":"HBEGF","synonyms":["DTS","DTSF","HEGFL","DTR"],"name":"heparin-binding EGF-like growth factor","description":"Enables growth factor activity; heparin binding activity; and transmembrane receptor protein tyrosine kinase activator activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and positive regulation of wound healing. Located in cell surface. Is active in extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":1839,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/1839","proteins":[{"symbol":"HBEGF_HUMAN","href":"/api/1.0/protein/HBEGF_HUMAN"}],"hgncRootFamilies":[]}