{"symbol":"HDGFL2","synonyms":[],"name":"HDGF like 2","description":"This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]","ncbiEntrezGeneId":84717,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gove/gene/84717","proteins":[],"hgncRootFamilies":[]}