{"symbol":"HEPACAM2","synonyms":["MIKI"],"name":"HEPACAM family member 2","description":"This gene encodes a protein related to the immunoglobulin superfamily that plays a role in mitosis. Knockdown of this gene results in prometaphase arrest, abnormal nuclear morphology and apoptosis. Poly(ADP-ribosylation) of the encoded protein promotes its translocation to centrosomes, which may stimulate centrosome maturation. A chromosomal deletion including this gene may be associated with myeloid leukemia and myelodysplastic syndrome in human patients. [provided by RefSeq, Oct 2016]","ncbiEntrezGeneId":253012,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/253012","proteins":[{"symbol":"HECA2_HUMAN","href":"/api/1.0/protein/HECA2_HUMAN"}],"hgncRootFamilies":[{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}