{"symbol":"HEYL","synonyms":["HRT3","BHLHB33","HEY3","HESR3"],"name":"hes-related family bHLH transcription factor with YRPW motif-like","description":"This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":26508,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/26508","proteins":[{"symbol":"HEYL_HUMAN","href":"/api/1.0/protein/HEYL_HUMAN"}],"hgncRootFamilies":[{"name":"Basic helix-loop-helix proteins (BHLH)","href":"/api/1.0/gene_family/Basic+helix-loop-helix+proteins+%28BHLH%29"}]}