{"symbol":"HIC2","synonyms":["ZBTB30","HRG22","ZNF907"],"name":"hypermethylated in cancer 2","description":"Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":23119,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23119","proteins":[{"symbol":"HIC2_HUMAN","href":"/api/1.0/protein/HIC2_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"},{"name":"BTB (POZ) domain containing (BTBD)","href":"/api/1.0/gene_family/BTB+%28POZ%29+domain+containing+%28BTBD%29"}]}