{"symbol":"HIST2H2BF","synonyms":[],"name":"histone cluster 2, H2bf","description":"Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family and is found in a histone cluster on chromosome 1. [provided by RefSeq, Aug 2015]","ncbiEntrezGeneId":440689,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/440689","proteins":[{"symbol":"H2B2F_HUMAN","href":"/api/1.0/protein/H2B2F_HUMAN"}],"hgncRootFamilies":[{"name":"Histones","href":"/api/1.0/gene_family/Histones"}]}