{"symbol":"HMBOX1","synonyms":["HOT1","HNF1LA","PBHNF"],"name":"homeobox containing 1","description":"Enables double-stranded telomeric DNA binding activity; identical protein binding activity; and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; telomere maintenance via telomerase; and telomere-telomerase complex assembly. Located in several cellular components, including centrosome; chromosome, telomeric region; and nuclear body. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":79618,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79618","proteins":[{"symbol":"HMBX1_HUMAN","href":"/api/1.0/protein/HMBX1_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}