{"symbol":"HOXA1","synonyms":["HOX1F","BSAS"],"name":"homeobox A1","description":"In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3198,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3198","proteins":[{"symbol":"HXA1_HUMAN","href":"/api/1.0/protein/HXA1_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}