{"symbol":"HOXB3","synonyms":["HOX-2.7","HOX2G"],"name":"homeobox B3","description":"This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3213,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3213","proteins":[{"symbol":"HXB3_HUMAN","href":"/api/1.0/protein/HXB3_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}