{"symbol":"HOXB4","synonyms":["HOX-2.6","HOX2F"],"name":"homeobox B4","description":"This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3214,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3214","proteins":[{"symbol":"HXB4_HUMAN","href":"/api/1.0/protein/HXB4_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}