{"symbol":"HOXB6","synonyms":["HOX-2.2","HOX2B","HU-2"],"name":"homeobox B6","description":"This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3216,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3216","proteins":[{"symbol":"HXB6_HUMAN","href":"/api/1.0/protein/HXB6_HUMAN"}],"hgncRootFamilies":[{"name":"Homeoboxes","href":"/api/1.0/gene_family/Homeoboxes"}]}