{"symbol":"HPR","synonyms":["A-259H10.2","HP"],"name":"haptoglobin-related protein","description":"This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer. [provided by RefSeq, Oct 2011]","ncbiEntrezGeneId":3250,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3250","proteins":[{"symbol":"HPTR_HUMAN","href":"/api/1.0/protein/HPTR_HUMAN"}],"hgncRootFamilies":[]}