{"symbol":"HRH4","synonyms":["AXOR35","BG26","GPRV53","H4R","GPCR105","HH4R"],"name":"histamine receptor H4","description":"Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]","ncbiEntrezGeneId":59340,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/59340","proteins":[{"symbol":"HRH4_HUMAN","href":"/api/1.0/protein/HRH4_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}