{"symbol":"HS3ST1","synonyms":["3OST1","3OST"],"name":"heparan sulfate (glucosamine) 3-O-sulfotransferase 1","description":"Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It possesses both heparan sulfate glucosaminyl 3-O-sulfotransferase activity, anticoagulant heparan sulfate conversion activity, and is a rate limiting enzyme for synthesis of anticoagulant heparan. This enzyme is an intraluminal Golgi resident protein. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":9957,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9957","proteins":[{"symbol":"HS3S1_HUMAN","href":"/api/1.0/protein/HS3S1_HUMAN"}],"hgncRootFamilies":[{"name":"Sulfotransferases","href":"/api/1.0/gene_family/Sulfotransferases"}]}