{"symbol":"HS3ST3A1","synonyms":["3-OST-3A","3OST3A1"],"name":"heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1","description":"Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta. [provided by RefSeq, Dec 2014]","ncbiEntrezGeneId":9955,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9955","proteins":[{"symbol":"HS3SA_HUMAN","href":"/api/1.0/protein/HS3SA_HUMAN"}],"hgncRootFamilies":[{"name":"Sulfotransferases","href":"/api/1.0/gene_family/Sulfotransferases"}]}