{"symbol":"HSD17B3","synonyms":["SDR12C2","EDH17B3"],"name":"hydroxysteroid (17-beta) dehydrogenase 3","description":"This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone.  It preferentially uses NADP as cofactor.  Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3293,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3293","proteins":[{"symbol":"DHB3_HUMAN","href":"/api/1.0/protein/DHB3_HUMAN"}],"hgncRootFamilies":[{"name":"Short chain dehydrogenase/reductase superfamily (SDR)","href":"/api/1.0/gene_family/Short+chain+dehydrogenase%24slash%24reductase+superfamily+%28SDR%29"}]}