{"symbol":"HTR3D","synonyms":["5HT3D"],"name":"5-hydroxytryptamine (serotonin) receptor 3D, ionotropic","description":"The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]","ncbiEntrezGeneId":200909,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/200909","proteins":[{"symbol":"5HT3D_HUMAN","href":"/api/1.0/protein/5HT3D_HUMAN"}],"hgncRootFamilies":[{"name":"5-hydroxytryptamine (serotonin) receptors (HTR)","href":"/api/1.0/gene_family/5-hydroxytryptamine+%28serotonin%29+receptors+%28HTR%29"},{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}