{"symbol":"HTR6","synonyms":["5-HT6","5-HT6R"],"name":"5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled","description":"This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013]","ncbiEntrezGeneId":3362,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3362","proteins":[{"symbol":"5HT6R_HUMAN","href":"/api/1.0/protein/5HT6R_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"},{"name":"5-hydroxytryptamine (serotonin) receptors (HTR)","href":"/api/1.0/gene_family/5-hydroxytryptamine+%28serotonin%29+receptors+%28HTR%29"}]}