{"symbol":"IFIT5","synonyms":["ISG58","RI58"],"name":"interferon-induced protein with tetratricopeptide repeats 5","description":"Enables nucleic acid binding activity. Involved in defense response to virus; negative regulation of viral genome replication; and positive regulation of canonical NF-kappaB signal transduction. Located in several cellular components, including IkappaB kinase complex; actin cytoskeleton; and ruffle membrane. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":24138,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/24138","proteins":[{"symbol":"IFIT5_HUMAN","href":"/api/1.0/protein/IFIT5_HUMAN"}],"hgncRootFamilies":[{"name":"Tetratricopeptide repeat domain containing (TTC)","href":"/api/1.0/gene_family/Tetratricopeptide+repeat+domain+containing+%28TTC%29"}]}