{"symbol":"IFNG","synonyms":["IFI","IFG"],"name":"interferon, gamma","description":"This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]","ncbiEntrezGeneId":3458,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3458","proteins":[{"symbol":"IFNG_HUMAN","href":"/api/1.0/protein/IFNG_HUMAN"}],"hgncRootFamilies":[{"name":"Interferons (IFN)","href":"/api/1.0/gene_family/Interferons+%28IFN%29"}]}