{"symbol":"IGF1","synonyms":["IGFI","IGF1A","IGF","IGF-I"],"name":"insulin-like growth factor 1 (somatomedin C)","description":"The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]","ncbiEntrezGeneId":3479,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3479","proteins":[{"symbol":"IGF1_HUMAN","href":"/api/1.0/protein/IGF1_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"}]}