{"symbol":"IKBKE","synonyms":["IKK-E","IKKE","IKK-I","IKKI"],"name":"inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon","description":"IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009]","ncbiEntrezGeneId":9641,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9641","proteins":[{"symbol":"IKKE_HUMAN","href":"/api/1.0/protein/IKKE_HUMAN"}],"hgncRootFamilies":[]}