{"symbol":"IL11RA","synonyms":["CRSDA"],"name":"interleukin 11 receptor, alpha","description":"Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]","ncbiEntrezGeneId":3590,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3590","proteins":[{"symbol":"I11RA_HUMAN","href":"/api/1.0/protein/I11RA_HUMAN"}],"hgncRootFamilies":[{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"},{"name":"Interleukin receptors","href":"/api/1.0/gene_family/Interleukin+receptors"}]}