{"symbol":"IL17RB","synonyms":["IL17BR","EVI27","IL17RH1","CRL4"],"name":"interleukin 17 receptor B","description":"The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":55540,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55540","proteins":[{"symbol":"I17RB_HUMAN","href":"/api/1.0/protein/I17RB_HUMAN"}],"hgncRootFamilies":[{"name":"Interleukin receptors","href":"/api/1.0/gene_family/Interleukin+receptors"}]}