{"symbol":"IL1R1","synonyms":["CD121A","IL-1R-ALPHA","IL1RA","IL1R","D2S1473","P80"],"name":"interleukin 1 receptor, type I","description":"This gene encodes a cytokine receptor that belongs to the interleukin-1 receptor family. The encoded protein is a receptor for interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist. It is an important mediator involved in many cytokine-induced immune and inflammatory responses. This gene is located in a cluster of related cytokine receptor genes on chromosome 2q12. [provided by RefSeq, Dec 2013]","ncbiEntrezGeneId":3554,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3554","proteins":[{"symbol":"IL1R1_HUMAN","href":"/api/1.0/protein/IL1R1_HUMAN"}],"hgncRootFamilies":[{"name":"Interleukin receptors","href":"/api/1.0/gene_family/Interleukin+receptors"},{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}