{"symbol":"IL1RAP","synonyms":["C3ORF13","IL1R3","IL-1RACP"],"name":"interleukin 1 receptor accessory protein","description":"This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]","ncbiEntrezGeneId":3556,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3556","proteins":[{"symbol":"IL1AP_HUMAN","href":"/api/1.0/protein/IL1AP_HUMAN"}],"hgncRootFamilies":[{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"},{"name":"Interleukin receptors","href":"/api/1.0/gene_family/Interleukin+receptors"}]}