{"symbol":"ING1","synonyms":["P24ING1C","P33ING1B","P47ING1A","P33ING1"],"name":"inhibitor of growth family, member 1","description":"This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3621,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3621","proteins":[{"symbol":"ING1_HUMAN","href":"/api/1.0/protein/ING1_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}