{"symbol":"INTS6","synonyms":["DDX26A","DICE1","DBI-1","NOTCHL2","DDX26","HDB"],"name":"integrator complex subunit 6","description":"DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3\u0027 end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2015]","ncbiEntrezGeneId":26512,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/26512","proteins":[{"symbol":"INT6_HUMAN","href":"/api/1.0/protein/INT6_HUMAN"}],"hgncRootFamilies":[{"name":"DEAD box polypeptides (DDX)","href":"/api/1.0/gene_family/DEAD+box+polypeptides+%28DDX%29"}]}