{"symbol":"IRS4","synonyms":["IRS-4","PY160"],"name":"insulin receptor substrate 4","description":"IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":8471,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8471","proteins":[{"symbol":"IRS4_HUMAN","href":"/api/1.0/protein/IRS4_HUMAN"}],"hgncRootFamilies":[]}