{"symbol":"ISG20","synonyms":["HEM45"],"name":"interferon stimulated exonuclease gene 20kDa","description":"Enables 3\u0027-5\u0027 exonuclease activity and RNA binding activity. Involved in defense response to virus; negative regulation of viral genome replication; and nucleobase-containing compound catabolic process. Located in cytoplasm and nuclear lumen. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":3669,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3669","proteins":[{"symbol":"ISG20_HUMAN","href":"/api/1.0/protein/ISG20_HUMAN"}],"hgncRootFamilies":[{"name":"Exonucleases","href":"/api/1.0/gene_family/Exonucleases"}]}