{"symbol":"ITGA1","synonyms":["CD49A","VLA1"],"name":"integrin, alpha 1","description":"This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":3672,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3672","proteins":[{"symbol":"ITA1_HUMAN","href":"/api/1.0/protein/ITA1_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Integrins (ITG)","href":"/api/1.0/gene_family/Integrins+%28ITG%29"}]}