{"symbol":"ITGA10","synonyms":["PRO827"],"name":"integrin, alpha 10","description":"Integrins are integral transmembrane glycoproteins composed of noncovalently linked alpha and beta chains. They participate in cell adhesion as well as cell-surface mediated signalling. This gene encodes an integrin alpha chain and is expressed at high levels in chondrocytes, where it is transcriptionally regulated by AP-2epsilon and Ets-1. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]","ncbiEntrezGeneId":8515,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8515","proteins":[{"symbol":"ITA10_HUMAN","href":"/api/1.0/protein/ITA10_HUMAN"}],"hgncRootFamilies":[{"name":"Integrins (ITG)","href":"/api/1.0/gene_family/Integrins+%28ITG%29"}]}