{"symbol":"ITGA2","synonyms":["GPIA","BR","CD49B","HPA-5","VLA-2","VLAA2"],"name":"integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)","description":"This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]","ncbiEntrezGeneId":3673,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3673","proteins":[{"symbol":"ITA2_HUMAN","href":"/api/1.0/protein/ITA2_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Integrins (ITG)","href":"/api/1.0/gene_family/Integrins+%28ITG%29"}]}