{"symbol":"JADE1","synonyms":["PHF17"],"name":"jade family PHD finger 1","description":"Enables transcription coactivator activity. Contributes to histone acetyltransferase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; regulation of cell growth; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle. Located in several cellular components, including cytosol; microtubule organizing center; and nuclear speck. Part of histone acetyltransferase complex. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":79960,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79960","proteins":[{"symbol":"JADE1_HUMAN","href":"/api/1.0/protein/JADE1_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}