{"symbol":"JAM2","synonyms":["VE-JAM","C21ORF43","JAM-B","PRO245","VEJAM","CD322","JAMB"],"name":"junctional adhesion molecule 2","description":"This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]","ncbiEntrezGeneId":58494,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/58494","proteins":[{"symbol":"JAM2_HUMAN","href":"/api/1.0/protein/JAM2_HUMAN"}],"hgncRootFamilies":[{"name":"CD molecules (CD)","href":"/api/1.0/gene_family/CD+molecules+%28CD%29"},{"name":"Immunoglobulin superfamily domain containing","href":"/api/1.0/gene_family/Immunoglobulin+superfamily+domain+containing"}]}