{"symbol":"JPH2","synonyms":["JP-2","CMH17"],"name":"junctophilin 2","description":"Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":57158,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/57158","proteins":[{"symbol":"JPH2_HUMAN","href":"/api/1.0/protein/JPH2_HUMAN"}],"hgncRootFamilies":[]}