{"symbol":"JUNB","synonyms":["AP-1"],"name":"jun B proto-oncogene","description":"Enables sequence-specific double-stranded DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of transcription factor AP-1 complex. Implicated in head and neck squamous cell carcinoma and melanoma. Biomarker of gastrointestinal system cancer (multiple); lung non-small cell carcinoma; and lymphoma (multiple). [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":3726,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/3726","proteins":[{"symbol":"JUNB_HUMAN","href":"/api/1.0/protein/JUNB_HUMAN"}],"hgncRootFamilies":[{"name":"Basic leucine zipper proteins","href":"/api/1.0/gene_family/Basic+leucine+zipper+proteins"}]}