{"symbol":"KAT2A","synonyms":["GCN5L2","HGCN5","GCN5","PCAF-B"],"name":"K(lysine) acetyltransferase 2A","description":"KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009]","ncbiEntrezGeneId":2648,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/2648","proteins":[{"symbol":"KAT2A_HUMAN","href":"/api/1.0/protein/KAT2A_HUMAN"}],"hgncRootFamilies":[{"name":"Chromatin-modifying enzymes","href":"/api/1.0/gene_family/Chromatin-modifying+enzymes"}]}