{"symbol":"KAT5","synonyms":["HTATIP","HTATIP1","CPLA2","PLIP","TIP60"],"name":"K(lysine) acetyltransferase 5","description":"The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10524,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10524","proteins":[{"symbol":"KAT5_HUMAN","href":"/api/1.0/protein/KAT5_HUMAN"}],"hgncRootFamilies":[{"name":"Chromatin-modifying enzymes","href":"/api/1.0/gene_family/Chromatin-modifying+enzymes"},{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}