{"symbol":"KATNB1","synonyms":["LIS6"],"name":"katanin p80 (WD repeat containing) subunit B 1","description":"Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10300,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10300","proteins":[{"symbol":"KTNB1_HUMAN","href":"/api/1.0/protein/KTNB1_HUMAN"}],"hgncRootFamilies":[{"name":"WD repeat domain containing (WDR)","href":"/api/1.0/gene_family/WD+repeat+domain+containing+%28WDR%29"}]}